Evaluation of diagnostic tests for Clostridium difficile infection.

نویسندگان

  • Jonathan Swindells
  • Nigel Brenwald
  • Nathan Reading
  • Beryl Oppenheim
چکیده

We evaluated toxigenic Clostridium difficile detection by a lateral flow assay for antigen and toxin, an enzyme immunoassay, and two commercial PCR methods. Compared to the cell cytotoxicity neutralization assay and toxigenic culture, both toxin detection methods lacked sensitivity. PCR following combined antigen and toxin detection provided the most useful diagnostic information.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 48 2  شماره 

صفحات  -

تاریخ انتشار 2010